Our laboratory is focussed on not only understanding NVC decline in disease but also in the development of novel therapies that target the cerebrovascular system to slow down or halt disease progression. My position was made permanent in 2007 and our research has now expanded to investigate in neurodegenerations with a particular focus on Alzheimer’s disease and focal cortical epilepsy.
This mechanism provides the image contrast for modern neuroimaging technologies such as functional magnetic resonance imaging (fMRI) and the early focus of the research was to understand NVC in order to provide a better understanding and interpretation of fMRI signals. Our research uses multimodal imaging and electrophysiological techniques to measure a mechanism in the brain called Neurovascular coupling (NVC). I joined the Department of Psychology in 1996 as a PhD student in the laboratory of Professor John Mayhew.